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Deoxyribose Nucleic Acid Values in Tumour Cells with Reference to the Stem-cell Theory of Tumour Growth

Abstract

RECENT technical developments have increased the accuracy and scope of photometric measurements of deoxyribose nucleic acid on Feulgen-stained nuclei. By using the scanning photoelectric device1,2 in conjunction with the cell-crushing method3, it is possible to make accurate measurements not only on interphase nuclei, but also on cells in mitosis. It has been shown that increase of deoxyribose nucleic acid occurs during interphase4,5. Hence measurements of the deoxyribose nucleic acid during mitotic stages are not subject to variation due to this synthesis.

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RICHARDS, B. Deoxyribose Nucleic Acid Values in Tumour Cells with Reference to the Stem-cell Theory of Tumour Growth. Nature 175, 259–261 (1955). https://doi.org/10.1038/175259a0

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