Abstract
IN 1932, Kettle published experimental results which suggested that the fibrogenic activity of silica in silicosis is due to silicic acid formed when the inhaled dust dissolves in tissue fluids. Since that time, the dissolution of silica and mineral silicates in water and physiological fluids has been widely studied in laboratories concerned with pneumoconiosis research.
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HOLT, P., KING, D. Solubility of Silica. Nature 175, 514–515 (1955). https://doi.org/10.1038/175514a0
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DOI: https://doi.org/10.1038/175514a0