Abstract
IT has long been known that large doses of acetylcholine may cause a neuromuscular block1. This block has been thought to be due to the ability of acetylcholine to depolarize persistently the end-plate regions of the muscle fibres2. No direct studies on the relation of such a neuromuscular block to the muscle membrane potential have, however, been carried out.
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References
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THESLEFF, S. Neuromuscular Block caused by Acetylcholine. Nature 175, 594–595 (1955). https://doi.org/10.1038/175594b0
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DOI: https://doi.org/10.1038/175594b0
