Abstract
IN the course of a study on factors that may be involved in the in vivo destruction of stored red cells, an experiment was performed which suggests that the antigenicity of red cells is altered when blood is kept for a long period of time under standard storage conditions, and individuals may be sensitized with such stored red cells.
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This is the 125-ml. size of a type of bottle in routine use for storing blood. Contained 40 ml. of ACD solution of following compositions: 1.38 gm. dextrose, 1.24 gm. sodium citrate and 0.45 gm. citric acid per 100 ml. Manufactured by Baxter Laboratories, Morton Grove, Illinois.
Wright, C. S., et al., J. Lab. and Clin. Med., 41, 169 (1953).
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MOSKOWITZ, M. Antibody Formation in Humans against their own Stored Red Cells. Nature 175, 595–596 (1955). https://doi.org/10.1038/175595b0
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DOI: https://doi.org/10.1038/175595b0
