Abstract
GLYCERIDES of known structure are usually prepared by blocking one or two hydroxyls of glycerol and esterifying the remaining hydroxyl or hydroxyls with fatty-acid chlorides. Thus monoglycerides are obtained by the action of a fatty-acid chloride on acetone–glycerol according to the well-known method of Fischer et al. 1, whereas mixed di- and tri-glycerides have been synthesized by Verkade and co-workers2 by the use of triphenyl-chloro-methane.
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References
Fischer, E., Bergmann, M., and Bärwind, H., Ber., 53, 1589 (1920).
cf. Verkade, P. E., Chimie et Industrie, 69, 239 (1953).
Grün, A., and Skopnik, A., Ber., 42, 3750 (1909). Malkin, T., Shurbagy, M. R., and Meara, M. L., J. Chem. Soc., 1409 (1937).
Verkade, P. E., Rec. Trav. Chim., 62, 393 (1943).
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HARTMAN, L. A Simplified Method of preparing Pure Mono-, Di- and Tri-glycerides. Nature 176, 1024 (1955). https://doi.org/10.1038/1761024a0
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DOI: https://doi.org/10.1038/1761024a0