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A Simplified Method of preparing Pure Mono-, Di- and Tri-glycerides

Abstract

GLYCERIDES of known structure are usually prepared by blocking one or two hydroxyls of glycerol and esterifying the remaining hydroxyl or hydroxyls with fatty-acid chlorides. Thus monoglycerides are obtained by the action of a fatty-acid chloride on acetone–glycerol according to the well-known method of Fischer et al. 1, whereas mixed di- and tri-glycerides have been synthesized by Verkade and co-workers2 by the use of triphenyl-chloro-methane.

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References

  1. Fischer, E., Bergmann, M., and Bärwind, H., Ber., 53, 1589 (1920).

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  2. cf. Verkade, P. E., Chimie et Industrie, 69, 239 (1953).

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  3. Grün, A., and Skopnik, A., Ber., 42, 3750 (1909). Malkin, T., Shurbagy, M. R., and Meara, M. L., J. Chem. Soc., 1409 (1937).

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  4. Verkade, P. E., Rec. Trav. Chim., 62, 393 (1943).

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HARTMAN, L. A Simplified Method of preparing Pure Mono-, Di- and Tri-glycerides. Nature 176, 1024 (1955). https://doi.org/10.1038/1761024a0

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