Abstract
Bell, Archer and Tomlin1, using the thromboplastin generation test, recently found the prolonged clotting time of horse blood to be due to a deficiency of anti-hæmophilic factor. However, Soulier and Larrieu2 have used horse plasma as a source of this factor. The thrombin generation test3,4 is useful in differentiating between classical hæmophilia and Christmas disease5. Applied to citrated horse plasma (containing 130,000 platelets per c.mm.) the following results were obtained (Fig. 1).
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Bell, W. N., Archer, R. K., and Tomlin, S. C., Nature, 175, 596 (1955).
Soulier, J. P., and Larrieu, M. J., J. Lab. Clin. Med., 41, 849 (1953).
Macfarlane, R. G., and Biggs, R., J. Clin. Path., 6, 9 (1953).
Pitney, W. R., and Dacie, J. V., J. Clin. Path., 6, 9 (1953).
Sjølin, K.-E., Scand. J. Lab. Clin. Invest. (in the press).
Aggeler, P. M., Spaet, T. H., and Byron, E. E., Science, 119, 806 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SJØLIN, KE. Lack of Christmas Factor in Horse Plasma. Nature 178, 153 (1956). https://doi.org/10.1038/178153a0
Issue date:
DOI: https://doi.org/10.1038/178153a0
