Abstract
THE elastolytic enzyme of human and animal pancreas which we have named elastase1–4 seemed to be specific for elastic fibre5, but apparently had no effect on native collagen fibre. Hall, Reed and Tunbridge6 have shown that elastase preparations have some effect on the mucopolysaccharide of elastin also, and during digestion sulphate and polysaccharide components are split off from elastin. Hall7 suggests the existence of two enzymes acting on elastin, having evidence that one of these must be regarded as a mucolytic one. Partridge and Davis8 determined the release of N-terminal residues from elastin by elastase and concluded that elastase preparation contains a proteolytic component also.
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References
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BANGA, I., BALÓ, J. Elastomucoproteinase and Collagen-mucoproteinase, the Mucolytic Enzymes of the Pancreas. Nature 178, 310–311 (1956). https://doi.org/10.1038/178310b0
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DOI: https://doi.org/10.1038/178310b0
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