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Bactericidal Action of Oleic Acid against Mycobacterium avium

Abstract

THERE have been many investigations of the bactericidal action of unsaturated fatty acids against tubercle bacilli1; but the mechanism of the effect still remains obscure. I have examined the action of oleic acid on Mycobacterium avium (Takeo strain) by Warburg and Thunberg's method, colony count and electron microscope.

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References

  1. Boissevain, C. H., Amer. Rev. Tub., 13, 84 (1926). Bergström, S., Theorell, H., and Davide, H., Nature, 157, 306 (1946). Davis, B. D., and Dubos, R. J., J. Bact., 55, 11 (1948).

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  2. Yamane, I., Hyodo, S., Honda, T., and Kadoya, K., Fukushima J. Med. Sci., Japan, 2, 35 (1955).

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  3. Lembke, A., and Ruska, H., Klin. Wschr., 19, 217 (1940). Brieger, E. M., Cosslett, V. E., and Glauert, A. M., J. Gen. Microbiol., 10, 294 (1954).

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MINAMI, K. Bactericidal Action of Oleic Acid against Mycobacterium avium . Nature 178, 743 (1956). https://doi.org/10.1038/178743a0

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