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‘Erythrocytin’ and ‘Erythrochelatin’

Abstract

IN a recent communication1, Beckett and Smith have described a thermolabile inhibitor acting on 8-hydroxyquinoline (‘Oxine’), which is either liberated or produced by erythrocytes and for which they have proposed the term ‘erythrocytin’. To avoid confusion, my associates and I wish to direct attention to the fact that we have applied the same name to the clotting factor which we discovered in the erythrocytes2. This, agent resembles the clotting principle occurring in the platelets, but is considerably more potent and has properties sufficiently characteristic to warrant regarding it as a distinct substance. We considered the name ‘erythrocytin’ particularly suitable because the ending ‘in’ is the same as in thromboplastin. The term has been employed in several of our publications3–5 during the past year and in the titles of two of these communications3,4.

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References

  1. Beckett, A. H., and Smith, W. G., Nature, 178, 742 (1956).

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  2. Georgatsos, J. G., Hussey, C. V., and Quick, A. J., Amer. J. Physiol., 181, 30 (1955). Quick, A. J., Georgatsos, J. G., and Hussey, C. V., Amer. J. Med. Sci., 228, 207 (1954).

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  3. Hussey, C. V., and Kaser, M., Fed. Proc., 15, 279 (1956).

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  4. Quick, A. J., and Hussey, C. V., J. Lab. and Clin. Med., 46, 940 (1955).

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  5. Quick, A. J., and Hussey, C. V., Amer. Med. Assoc. Arch. Int. Med., 97, 524 (1956).

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QUICK, A. ‘Erythrocytin’ and ‘Erythrochelatin’. Nature 179, 54 (1957). https://doi.org/10.1038/179054b0

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