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Identity of ‘Nudic Acid B’ and ‘Diatretyne II’

Nature volume 179, page 1078 (1957)Cite this article

Abstract

IN 1946 two crystalline acidic antibiotics (‘nudic acids A and B’) were isolated from the culture medium of the basidiomycete Tricholoma nudum (Bull.) Fr. and some preliminary work on their respective constitutions was carried out1. It has now been shown that ‘nudic acid B’ is identical with ‘diatretyne II’ (7-cyano-trans-hept-2-en-4 : 6-diynoic acid (I)), which is produced by another fungus, Clitocybe diatreta 2, and which has been obtained synthetically (Ashworth, Jones, Mansfield, Schlögl, Thompson and Whiting, unpublished work).

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References

  1. Florey, Chain, Heatley, Jennings, Sanders, Abraham and Florey, “Antibiotics”, 358, (Oxford University Press, 1949).

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  2. Anchel, Science, 121, 607 (1955).

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Authors and Affiliations

  1. Sir William Dunn School of Pathology, Oxford

    N. G. HEATLEY

  2. The Dyson Perrins Laboratory, Oxford

    J. S. STEPHENSON

Authors
  1. N. G. HEATLEY
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  2. J. S. STEPHENSON
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HEATLEY, N., STEPHENSON, J. Identity of ‘Nudic Acid B’ and ‘Diatretyne II’. Nature 179, 1078 (1957). https://doi.org/10.1038/1791078a0

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