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Cytopathogenicity of Rinderpest Virus in Tissue Culture

Abstract

Takematsu and Morimoto1 have reported cultivation of lapinized rinderpest virus in roller-tube cultures of rabbit lymph node, spleen and bone marrow; but details are not available to us, and it is not known if cytopathological effects were observed. In this laboratory, we have found that the Kabete ‘O’ strain of virulent rinderpest virus multiplies in mono-layers of bovine embryonic kidney cells and produces characteristic cytological changes. In addition, kidney-passaged virus destroys bovine fibroblasts grown from embryonic skin-muscle tissue and prepubertal testis.

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References

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PLOWRIGHT, W., FERRIS, R. Cytopathogenicity of Rinderpest Virus in Tissue Culture. Nature 179, 316 (1957). https://doi.org/10.1038/179316a0

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