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Effect of Radioactive Colloidal Gold on the Mast Cells of Bone Marrow

Abstract

AN increase in the number of mast cells has been reported in the thymus, spleen and bone marrow of mice exposed to long-continued gamma irradiation1. Hypoplasia of the bone marrow has been reported in animals and man following the administration of radioactive colloidal gold (gold-198)2, but no reference is made to any change in the mast cells. In the course of an investigation of the general histo-pathological effects of colloidal gold-198 administered to rats, we have found an increase in the mast cell population of the bone marrow.

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GUIMARAES, J., TAYLOR, D. Effect of Radioactive Colloidal Gold on the Mast Cells of Bone Marrow. Nature 179, 914–915 (1957). https://doi.org/10.1038/179914a0

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