Abstract
AN increase in the number of mast cells has been reported in the thymus, spleen and bone marrow of mice exposed to long-continued gamma irradiation1. Hypoplasia of the bone marrow has been reported in animals and man following the administration of radioactive colloidal gold (gold-198)2, but no reference is made to any change in the mast cells. In the course of an investigation of the general histo-pathological effects of colloidal gold-198 administered to rats, we have found an increase in the mast cell population of the bone marrow.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Sparge, B., et al., J. Nat. Cancer Inst., 12, 615 (1951).
Fisher, E. R., et al., Amer. J. Med. Sci., 223, 502 (1952). Jackson, A. H., and Hahn, P. F., Cancer, 8, 482 (1955). Botsford, T. H., et al., J. Amer. Med. Assoc., 151, 788 (1953).
Asboe-Hansen, G., Cancer Res., 13, 587 (1953).
Allen, J. G., and Jacobson, L. O., Science, 105, 383 (1947). Allen, J. G., et al., J. Exp. Med., 87, 71 (1948).
Kelsal, M. A., and Crabb, E. C., Science, 115, 123 (1952).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
GUIMARAES, J., TAYLOR, D. Effect of Radioactive Colloidal Gold on the Mast Cells of Bone Marrow. Nature 179, 914–915 (1957). https://doi.org/10.1038/179914a0
Issue date:
DOI: https://doi.org/10.1038/179914a0