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Influence of Metallic Ions on the Reaction of Ethylene Diamine with Epinephrine and Norepinephrine

Abstract

THE reaction of ethylene diamine with epinephrine (and norepinephrine) leads to the formation of a highly fluorescent material which is used for the estimation of catechol amines in biological fluids according to a procedure first described by Weil-Malherbe and Bone1 and slightly modified by a number of other workers.

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References

  1. Weil-Malherbe, H., and Bone, A. D., Biochem. J., 51, 311 (1952).

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  2. Erne, K., and Canbäck, T., J. Pharm. Pharmacol., 7, 248 (1955).

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  3. Valk, A. de T., and Price, H. L., J. Clin. Invest., 35, 837 (1956).

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  4. Mangan, G. F., and Mason, J. W., Science, 126, 562 (1957).

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NADEAU, G., JOLY, L. & SOBOLEWSKI, G. Influence of Metallic Ions on the Reaction of Ethylene Diamine with Epinephrine and Norepinephrine. Nature 181, 1061 (1958). https://doi.org/10.1038/1811061a0

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