Abstract
A RABBIT tolerant1 to a particular protein responds normally to an immunologically unrelated protein. Animals tolerant to one of two cross-reacting proteins respond badly or not at all to the other; this has been demonstrated with heterologous proteins, but may equally apply if one of the two cross-reacting proteins is autologous.
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CINADER, B., PEARCE, J. & CARTER, B. Acquired Immunological Tolerance to Bovine Ribonuclease. Nature 181, 1208–1209 (1958). https://doi.org/10.1038/1811208a0
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DOI: https://doi.org/10.1038/1811208a0
