Abstract
A RELATIONSHIP between the level of ribonuclease activity and ribonucleic acid content has recently been found to exist in the human placenta1 and in hyperplastic bone marrow of the mouse2; such a relationship has also been shown to exist in different normal organs of the mouse3, as well as different epitheliomas in mice or rats4. On the other hand, results obtained with solid4 and ascites tumours5 suggest that cancerous epithelium might have less ribonuclease activity than a normal one. We have undertaken a study of the properties of the human uterine cervix, from which homologous normal and cancerous tissues can easily be obtained.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Brody, S., Biochim. Biophys. Acta, 24, 502 (1957).
Brody, S., and Thorell, B., Biochim. Biophys. Acta, 25, 579 (1957).
Ledoux, L., Pileri, A., Vanderhaeghe, F., and Brändli, S., Nature, 180, 502 (1957).
Ledoux, L., Pileri, A., and Vanderhaeghe, F., Arch. intern. Physiol. et Biochim., 66, 124 (1958).
Ledoux, L., Pileri, A., and Vanderhaeghe, F., Arch. intern. Physiol. et Biochim., 66, 122 (1958).
Ledoux, L., Nature, 176, 36 (1955); Brit. J. Cancer (in the press).
Hadjiolov, A. A., and Zacharieva, L., Naturwiss., 44, 45 (1957).
Ledoux, L., and Vanderhaeghe, F., Biochim. Biophys. Acta, 24, 340 (1957).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
LEDOUX, L., BRÄNDLI, S. & DE PAEPE, J. Ribonuclease Activity and Ribonucleic Acid Content of Homologous Human Normal and Cancer Cells. Nature 181, 913–914 (1958). https://doi.org/10.1038/181913a0
Issue date:
DOI: https://doi.org/10.1038/181913a0
