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Difference between Lipoprotein Lipase and Post-Heparin Esterase in Human Serum

Nature volume 182, pages 117–118 (1958)Cite this article

Abstract

THE basic component of the clearing factor1 is a lipolytic enzyme which differs from hitherto known lipases2. Its lipolytic action can be demonstrated by the hydrolysis of the fatty components of lipoproteins3. When using β-naphthyl laurate4, acetylcholine and butyrylcholine5 as substrate the results are negative. With tributyrin the findings are conflicting6. If ethyl butyrate is used as substrate, raised esterolytic activity of the sera can be observed in man after the intravenous injection of heparin7.

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Authors and Affiliations

  1. Fourth Medical Clinic, Charles University, Prague

    J. SKOŘEPA & Š. NOVÁK

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  1. J. SKOŘEPA
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  2. Š. NOVÁK
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SKOŘEPA, J., NOVÁK, Š. Difference between Lipoprotein Lipase and Post-Heparin Esterase in Human Serum. Nature 182, 117–118 (1958). https://doi.org/10.1038/182117b0

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