Abstract
TETANUS toxin is thought to act by suppressing synaptic inhibition1, and presumably it acts upon some substance at the inhibitory synapses in the grey matter of nervous tissue. As a possible approach to discovering the nature of this substance, the well-known Wassermann–Takaki phenomenon2, that is, the fixation of tetanus toxin by the grey matter of nervous tissue, has been re-investigated.
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References
Brooks, V. B., Curtis, D. R., and Eccles, J. C., Nature, 175, 120 (1955).
Wassermann, A., and Takaki, T., Berl. klin. Wschr., 35, 5 (1898).
Landsteiner, K., and Botteri, A., Zbl. Bakt. Orig., 42, 562 (1906).
Lowry, O. H., Rosebrough, N. J., Farr, A. L., and Randall, R. J., J. Biol. Chem., 193, 265 (1951).
Pillemer, L., Wittler, R. G., Burrell, J. I., and Grossberg, D. B., J. Exp. Med., 88, 205 (1948).
Gregory, J. D., and Craig, L. C., J. Biol. Chem., 172, 839 (1948).
Rosenberg, A., and Chargaff, E., J. Biol. Chem., 232, 1031 (1958).
Klenk, E., in “Biochemistry of the Developing Nervous System”, 397 (Academic Press, Inc., New York, 1955).
Folch, J., Arsove, S., and Meath, J. A., J. Biol. Chem., 191, 819 (1951).
Dunn, M. S., Camien, M. N., and Pillemer, L., Arch. Biochem., 22, 374 (1949).
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VAN HEYNINGEN, W. Identity of the Tetanus Toxin Receptor in Nervous Tissue. Nature 182, 1809 (1958). https://doi.org/10.1038/1821809a0
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DOI: https://doi.org/10.1038/1821809a0