Abstract
THE effect of various transition elements on lipid and sterol metabolism has received attention in recent years1. For example, both vanadium and members of the rare-earth group are capable of producing a fatty infiltration of the liver. Furthermore, vanadium can cause a marked reduction in cholesterol and phospholipids1 2. In this connexion, work has been directed towards investigating a possible prophylactic action of vanadium against atherosclerosis2; it has been suggested that disruption of the endogenous balance of the transition elements in the liver could underlie the pathogenesis of this disease1.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Curran, G. L., J. Biol. Chem., 210, 765 (1954). Mountain, J. T., Stockwell, F. R., and Stokinger, H. E., Proc. Soc. Exp. Biol. Med., 92, 582 (1956).
Eades, C. H., and Gallo, D. G., Fed. Proc., 16, 176 (1957).
Bernheim, F., and Bernheim, M. L. C., J. Biol. Chem., 127, 353 (1939).
Mountain, J. T., Delker, L. L., and Stokinger, H. E., A.M.A. Arch. Indust. Hyg. Occup. Med., 8, 406 (1953).
Snyder, F., and Cornatzer, W. E., Proc. Soc. Exp. Biol. Med., 96, 670 (1957).
Snyder, F., and Cornatzer, W. E., J. Biol. Chem., 231, 839 (1958).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SNYDER, F., CORNATZER, W. Vanadium Inhibition of Phospholipid Synthesis and Sulphydryl Activity in Rat Liver. Nature 182, 462 (1958). https://doi.org/10.1038/182462a0
Issue date:
DOI: https://doi.org/10.1038/182462a0
