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Beta-globulin Polymorphism in Cattle, Sheep and Goats

Abstract

Detection by paper electrophoresis. Using starch gel electrophoresis, six cattle1, fourteen sheep2, three goat (see later) and three human3,4 β-globulin phenotypes have been recognized and indicated to be under the genetic control of three, five, two and three allelomorphs respectively. As one of us had noticed a variation in the number and position of the β-globulin zones in paper electrophoresis of animal sera, the two methods have been compared on sera from cattle, sheep and goats. Starch gel electrophoresis was carried out in phosphate buffer1 pH. 7.6, paper electrophoresis on a wide strip of horizontally suspended Whatman 3MM paper in barbiturate buffer pH 8.6, I 0.05. Typical examples of corresponding electropherograms of sheep and cattle sera are shown in Figs. 1 and 2. The electropherograms of goat sera shown in Fig. 3 are discussed below.

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References

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ASHTON, G., McDOUGALL, E. Beta-globulin Polymorphism in Cattle, Sheep and Goats. Nature 182, 945–946 (1958). https://doi.org/10.1038/182945a0

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