Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Different Types of Hæmoglobin in Two Strains of Mice

Abstract

WHILE studying the therapeutic effect of homologous bone marrow transplantation in irradiated mice we needed a simple and sensitive technique to differentiate between the hæmatopoietic activity of the host and that of the graft. The possibility of employing differences between the hæmoglobins of our two strains of mice (CBA and C57BL) and their hybrid was suggested by the findings of Ranney et al. 1,2, who demonstrated two different hæmoglobin patterns in eight inbred strains of mice by using paper electrophoresis.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Ranney, H. M., and Gluecksohn-Waelsch, S., Ann. Hum. Genetics, 19, 269 (1955).

    Article  CAS  Google Scholar 

  2. Gluecksohn-Waelsch, S., Ranney, H. M., and Sisken, B. F., J. Clin. Invest., 36, 753 (1957).

    Article  CAS  Google Scholar 

  3. Robinson, A. R., Robson, M., Harrison, A. P., and Zuelzer, W. W., J. Lab. Clin. Med., 50, 745 (1957).

    PubMed  CAS  Google Scholar 

  4. Jonxis, J. H. P., and Visser, H. K. A., Amer. J. Diseases of Children, 92, 588 (1956).

    CAS  Google Scholar 

  5. Itano, H. A., Fed. Proc., 16, 748 (1957).

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

WELLING, W., VAN BEKKUM, D. Different Types of Hæmoglobin in Two Strains of Mice. Nature 182, 946–947 (1958). https://doi.org/10.1038/182946b0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/182946b0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing