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Effect of Protein-free Diet on the Vitamin A Storage in the Rat Liver

Abstract

SEVERAL workers1–4 have reported that diets low in protein reduced the storage of vitamin A in the liver and increased the rate at which stored vitamin A was depleted. On the basis of such data, a conclusion was drawn by investigators that protein is a necessary dietary constituent for normal storage and utilization of vitamin A. The work described here was designed to test the validity of the former hypothesis by comparing hepatic vitamin A storage in young rats fed an 18 per cent casein diet and in animals fed a protein-free diet under the conditions of controlled intake of vitamin A.

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RECHCIGL, M., BERGER, S., LOOSLI, J. et al. Effect of Protein-free Diet on the Vitamin A Storage in the Rat Liver. Nature 183, 1597 (1959). https://doi.org/10.1038/1831597a0

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