Abstract
DURING the development of a screening test for goitrogenic activity of drugs, β-aminoethylisothiouronium dibromide, a radiation protective agent1, was observed to have anti-thyroid activity. In view of possible long-term administration of this substance for prophylactic protection against irradiation, we are reporting our findings.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Doherty, D. G., and Burnett, W. T., Proc. Soc. Exp. Biol. Med., 89, 312 (1955).
Taurog, A., Chaikoff, I. L., and Feller, D. D., J. Biol. Chem., 171, 189 (1947).
Smith, W. W., and Smith, F., Amer. J. Physiol., 165, 639 (1951).
Nygaard, O., and Eldjarn, L., Arch. Int. Physiol., 62, 528 (1954).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
OSMER, J., JENNINGS, R. & DOWBEN, R. Anti-Thyroid Action of β-Aminoethylisothiouronium Dibromide in Rats. Nature 183, 470 (1959). https://doi.org/10.1038/183470a0
Issue date:
DOI: https://doi.org/10.1038/183470a0