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Anti-Thyroid Action of β-Aminoethylisothiouronium Dibromide in Rats

Abstract

DURING the development of a screening test for goitrogenic activity of drugs, β-aminoethylisothiouronium dibromide, a radiation protective agent1, was observed to have anti-thyroid activity. In view of possible long-term administration of this substance for prophylactic protection against irradiation, we are reporting our findings.

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References

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OSMER, J., JENNINGS, R. & DOWBEN, R. Anti-Thyroid Action of β-Aminoethylisothiouronium Dibromide in Rats. Nature 183, 470 (1959). https://doi.org/10.1038/183470a0

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