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Oxidative Metabolism of Cartilage

Nature volume 183, pages 610–611 (1959)Cite this article

Abstract

ALTHOUGH utilization of oxygen by mature cartilage is very low, with Qo2 values ranging between 0 and 0.681–5, studies by Rosenthal, Bowie, and Wagoner6 and Boyd and Neuman7 have shown that embryonic cartilage utilizes significantly greater amounts of oxygen (Qo2, 2.2). Paradoxically, although dehydrogenases customarily mediated via cytochrome oxidase (that is, succinic and isocitric dehydrogenases) have been identified in both mature and embryonic cartilage1,8, until now the biochemical demonstration of cytochrome oxidase activity in cartilage had not been accomplished.

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Authors and Affiliations

  1. Special Dental Research Laboratory, Veterans Administration Hospital, Brooklyn, New York

    PHILIP PERSON & ALBERT FINE

  2. Marine Biological Laboratory, Woods Hole, Mass.

    PHILIP PERSON & ALBERT FINE

Authors
  1. PHILIP PERSON
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  2. ALBERT FINE
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PERSON, P., FINE, A. Oxidative Metabolism of Cartilage. Nature 183, 610–611 (1959). https://doi.org/10.1038/183610a0

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