Abstract
IN reviewing the literature of the hyperglobulinæmias one is struck by the frequency of the reports of a concomitant hæmorrhagic diathesis. In a survey by us of more than a thousand cases of macroglobulinæmia, cryoglobulinæmia, visceral leishmaniasis and miscellaneous hyperglobulinæmias, a hæmorrhagic diathesis was reported in 63–94 per cent of the cases in each category. These observations suggest that purpura is a general phenomenon in the presence of increased plasma globulins.
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References
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HENSTELL, H., KLIGERMAN, M. Hyperglobulinæmic Thrombo-Hæmorrhagic Diathesis. Nature 183, 978–979 (1959). https://doi.org/10.1038/183978a0
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DOI: https://doi.org/10.1038/183978a0