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α-Oxidation of Indoleacetonitrile

Abstract

IT is known that certain plant tissues can convert 3-indolylacetonitrile to the highly active plant growth substance 3-indolylacetic acid1–3 and we have shown that other plant tissues are able to bring about an α-oxidation of 3-indolylacetonitrile to yield 3-indolylcarboxylic acid which is inactive3,4. A recent publication by Thimann and Mahadevan5 describing the extraction of what is believed to be a hydrolytic enzyme from the stems and leaves of certain monocotyledons (Gramineae), which is capable of converting 3-indolylacetonitrile to 3-indolylacetic acid, prompts us to report upon experiments using a cell-free extract of etiolated stems of a dicotyledon (Pisum). A clear demonstration of the α-oxidation of 3-indolylacetonitrile to 3-indolylcarboxylic acid is given by this extract.

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References

  1. Thimann, K. V., Arch. Biochem. Biophys., 44, 242 (1953).

    Article  CAS  Google Scholar 

  2. Stowe, B. B., and Thimann, K. V., Arch. Biochem. Biophys., 51, 499 (1954).

    Article  CAS  Google Scholar 

  3. Seeley, R. C., Fawcett, C. H., Wain, R. L., and Wightman, F., ‘The Chemistry and Mode of Action of Plant Growth Substances’ (Butterworth's Publications, 1956).

    Google Scholar 

  4. Fawcett, C. H., Seeley, R. C., Taylor, H. F., Wain, R. L., and Wightman, F., Nature, 176, 1026 (1955).

    Article  ADS  CAS  Google Scholar 

  5. Thimann, K. V., and Mahadevan, S., Nature, 181, 1466 (1958).

    Article  ADS  CAS  Google Scholar 

  6. Fawcett, C. H., Taylor, H. F., Wain, R. L., and Wightman, F., Proc. Roy. Soc., B, 148, 543 (1958).

    Article  ADS  CAS  Google Scholar 

  7. Cartright, P. M., Sykes, J. T., and Wain, R. L., ‘The Chemistry and Mode of Action of Plant Growth Substances’ (Butterworth's Publications, 1956).

    Google Scholar 

  8. Jones, E. R. H., Henbest, H. B., Smith, G. F., and Bentley, J. A., Nature, 169, 485 (1952).

    Article  ADS  CAS  Google Scholar 

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TAYLOR, H., WAIN, R. α-Oxidation of Indoleacetonitrile. Nature 184, 1142 (1959). https://doi.org/10.1038/1841142a0

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