Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Glutathione Stability of the Erythrocytes in Iranians

Nature volume 184, page 1325 (1959)Cite this article

Abstract

HÆMOLYTIC reactions following the ingestion of drugs such as primaquine and the broad bean (Vicia faba) have been shown to be due to an inherited abnormality of the erythrocytes which can be detected by an in vitro glutathione stability test devised by Beutler1. The use of this test in surveys has established that the incidence of the defect varies with peoples and race. American Negroes, Sephardic Jews and Sardinians have a much higher incidence of sensitive individuals than Ashkenazic Jews or American Caucasians. Beutler has recently reviewed the subject2. Many cases of favism have been seen locally during the past few years, and it was reasonable to assume that a survey of the glutathione stability of the erythrocytes in Iranians would show the presence of the abnormality in this area.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on SpringerLink
  • Instant access to the full article PDF.

USD 39.95

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Beutler, E., J. Lab. and Clin. Med., 49, 84 (1957).

    CAS  Google Scholar 

  2. Beutler, E., Blood, 14, 103 (1959).

    Article  CAS  PubMed  Google Scholar 

  3. Szeinberg, A., Asher, Y., and Sheba, C., Blood, 13, 348 (1958).

    Article  CAS  PubMed  Google Scholar 

  4. Szeinberg, A., Sheba, C., and Adam, A., Blood, 13, 1043 (1958).

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry, Faculty of Medicine, University of Shiraz,

    D. G. WALKER

  2. Department of Pathology, Shiraz Medical Center, The Nemazee Hospital, Shiraz, Iran

    J. E. BOWMAN

Authors
  1. D. G. WALKER
    View author publications

    Search author on:PubMed Google Scholar

  2. J. E. BOWMAN
    View author publications

    Search author on:PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

WALKER, D., BOWMAN, J. Glutathione Stability of the Erythrocytes in Iranians. Nature 184, 1325 (1959). https://doi.org/10.1038/1841325a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/1841325a0

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing