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Influence of Sexual Stimulation on the Metabolic Activity of Deoxyribonucleic Acid in the Seminal Vesicle

Abstract

LABELLED adenine1 and thymidine labelled with tritium2 are incorporated into the deoxyribonucleic acid of the epithelial cells of the seminal vesicle of adult mice at a rate equivalent to a renewal of approximately 10 per cent of the deoxyribonucleic acid per day. Comparison of counts of cells in division and labelled nuclei in autoradiographs of the seminal vesicle and œsophagus2 show that this renewal of deoxyribonucleic acid is approximately 45 times in excess of requirements for cell-proliferation. It seemed of interest to explore whether this incorporation of thymidine is influenced by the sexual activity of the animals.

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References

  1. Pelc, S. R., Exp. Cell Res., 14, 301 (1958).

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  2. Pelc, S. R., Nature, 183, 335 (1959).

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  3. Schooley, J., Kelly, L. S., and (private communication).

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PELC, S. Influence of Sexual Stimulation on the Metabolic Activity of Deoxyribonucleic Acid in the Seminal Vesicle. Nature 184, 1414 (1959). https://doi.org/10.1038/1841414a0

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