Abstract
RECENTLY we have reported that sulphonamides with a substituted amido-group that is, compounds deprived of any inhibitory action on carbonic anhydrase, may possess a high diuretic activity1. The most active compound of the series is 4-amino-6-chloro-benzene-1,3-disulphonmethylamide (I).
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References
Logemann, W., Giraldi, P. N., and Parenti, M. A., Nature, 182, 1510 (1958). Logemann, W., Giraldi, P. N., and Galimberti, S., Liebigs Ann. Chem., 623, 157 (1959). Rulli, V., Bonami, L., and Concina, B., Il Policlinico (in the press). Parenti, M. A., Il Farmaco (in the press). Giraldi, P. N., Il Farmaco (in the press).
de Stevens, G., Werner, L. H., Halamandaris, A., and Ricca, S., jun., Experientia, 14, 463 (1958).
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LOGEMANN, W., GIRALDI, P. & PARENTI, M. Sulphonamides with Diuretic Activity. Nature 184, 1711 (1959). https://doi.org/10.1038/1841711a0
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DOI: https://doi.org/10.1038/1841711a0
