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Relation of Ethanol Metabolism to Several Factors in the Rat

Abstract

THE most important site for the oxidation of alcohol is the liver. Various experimental approaches, for example, the artificial perfusion of surviving liver with blood containing alcohol, oxidation of alcohol by liver slices and liver brei, diminished alcohol oxidation following either hepatectomy or damage to the liver, and the demonstration that the eviscerated animal metabolizes alcohol very slowly, have all indicated that the liver is of major importance in the metabolism of ethanol1.

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KINARD, F., AULL, J. & ULMER, R. Relation of Ethanol Metabolism to Several Factors in the Rat. Nature 184, 1721 (1959). https://doi.org/10.1038/1841721a0

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