Abstract
SODIUM salicylate is known to cause a loss of potassium from rat diaphragms1. It is also known to uncouple oxidative phosphorylation2, and it is suggested1 that the loss of potassium is due to an interference with the energy supplies for active transport. If so, the inward movement of potassium should be decreased in the presence of salicylate and the outward movement unaltered or decreased as the intracellular concentration of potassium falls.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Manchester, K. L., Randle, P. J., and Smith, G. H., Brit. Med. J. i, 1028 (1958).
Brody, T. M., J. Pharmacol. Exp. Therap., 117, 39 (1956).
Creese, R., Proc. Roy. Soc., B., 142, 497 (1954).
Harris, E. J., and Burn, G. P., Trans. Farad. Soc., 45, 508 (1949).
Rayner, B., and Weatherall, M., J. Physiol., 146, 392 (1959).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
HICKLIN, J. Salicylate and Potassium Fluxes of Rat Diaphragm. Nature 184, 2029 (1959). https://doi.org/10.1038/1842029a0
Issue date:
DOI: https://doi.org/10.1038/1842029a0
This article is cited by
-
Mitochondrial uncoupling agents
The Journal of Membrane Biology (1975)
-
Untersuchungen zur Beeinflussung des Stoffwechsels wachsender Schweine durch ein Salicylsäurederivat
Zeitschrift für Die Gesamte Experimentelle Medizin (1961)
-
Der Kalium-Flux des normalen und denervierten Rattenzwerchfells
Pfl�gers Archiv f�r die Gesamte Physiologie des Menschen und der Tiere (1960)
