Abstract
WE were led to look for the presence of this trait in Nigeria because of the demonstration that 10 per cent of American Negroes are deficient in this enzyme1 and the discovery that hæmolytic anæmia caused by certain drugs (for example, primaquine) develops only in the presence of this sex-linked inherited deficiency of red cell glucose-6-phosphate dehydro-genase2.
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References
Beutler, E., Blood, 14, 103 (1959).
Garson, P. E., Flanagan, C. L., Ickes, C. E., and Alving, A. S., Science, 124, 484 (1956). Szeinberg, A., Sheba, C., and Adam, A., Nature, 181, 1256 (1958). Gross, R. T., Hurwitz, R. E., and Marks, P. A., J. Clin. Invest., 37, 1176 (1958). Childs, B., Zinkham, W., Browns, E. A., Kimbro, R. L., and Torbert, J. V., Bull. Johns Hopkins Hosp., 102, 21 (1958).
Motulsky, A. G., and Campbell, J. M., Blood (in the press).
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GILLES, H., WATSON-WILLIAMS, J. & TAYLOR, B. Glucose-6-Phosphate Dehydrogenase Deficiency Trait in Nigeria. Nature 185, 257–258 (1960). https://doi.org/10.1038/185257b0
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DOI: https://doi.org/10.1038/185257b0
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