Abstract
WE have recently reported on the delay of whole-blood thrombin generation in vitro and in vivo which occurs when the concentration of magnesium is raised1,2. These results might have been thought to contradict the fact that addition of magnesium is known to enhance clotting of blood of which the calcium content has been lowered by previous passage through a suitable ion exchange column3.
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References
Anstall, H. B., Huntsman, R. G., Lehmann, H., Hayward, G. W., and Weitzman, D., Lancet, i, 814 (1959).
Huntsman, R. G., Hurn, B. A. L., and Lehmann, H., J. Clin. Path., 13, 88 (1960).
Soulier, J.-P., Proc. Seventh European Congress of Hæmatology 1959 (in the press).
Greville, G. D., and Lehmann, H., J. Physiol., 103, 175 (1943).
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HUNTSMAN, R., HURN, B. & LEHMANN, H. Paradoxical Effect of Magnesium Ions on Blood Coagulation. Nature 185, 852 (1960). https://doi.org/10.1038/185852a0
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DOI: https://doi.org/10.1038/185852a0
