Abstract
THE relatively small disturbance in the chemical component of thermoregulation in the rat1 after the injection of chlorpromazine cannot explain completely the expressive hypothermia observed with this drug2. LeBlanc presumes that the physical component of thermoregulation as the result of postural changes caused by chlorpromazine3,4 plays a significant part. In work presented in this communication, I have aimed at a closer definition of these postural changes and further at determining their relation to the changes of body temperature.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Courvoisier, S., Fournel, J., Ducrot, R., Kolsky, M., and Koetschet, P., Arch. Internat. Pharmacodyn., 92, 305 (1953).
Giaja, J., and Markovič-Giaja, L., C.R. Soc. Biol., 148, 842 (1954).
LeBlanc, J., J. App. Physiol., 13, 237 (1958).
Svorad, D., Symposium on Hypothermia, Belgrade, 161 (1959).
Svorad, D., Physiol. bohemoslov., 4, 170 (1955).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
SVORAD, D. Postural Changes in Chlorpromazine Hypothermia. Nature 186, 240–241 (1960). https://doi.org/10.1038/186240b0
Issue date:
DOI: https://doi.org/10.1038/186240b0
