Abstract
EXAMINATION of tissues stained for mast cells with a variety of accepted techniques has shown a need for a more specific staining method. The use of the conventional metachromatic dyes, though resulting in satisfactory preparations in many cases, presented problems of identification of mast cell granules in some tissues, for example, in lymph nodes where the intense nuclear orthochromatic staining of surrounding cells obscures metachromatic granules.
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References
Barlow, R. M., J. Path. Bact., 73, 272 (1957).
Radden, B. G., submitted to J. Histochem. Cytochem.
Radden, B. G., thesis accepted by the University of London for the degree of Ph.D. (1959).
Pearse, A. G.E., “Histochemistry. Theoretical and Applied”, 1st ed. (Little Brown and Co., Boston, 1953).
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RADDEN, B. A Specific Stain for Mast Cell Granules. Nature 186, 400–402 (1960). https://doi.org/10.1038/186400a0
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DOI: https://doi.org/10.1038/186400a0
