Abstract
RECENTLY I have attempted to develop a general theory of ageing applicable to mammals1. This theory assumes that, during the life-time of the animal, whole chromosomes, which are contained in the somatic cells, suffer a total loss of function in a single random event. It further assumes that the probability of such an event remains constant throughout life-time and that it is the same for all individuals of a given species.
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References
Szilard, Leo, Proc. U.S. Nat. Acad. Sci., 45, 32 (1959).
Tijo, J. H., and Puck, T. T., Proc. U.S. Nat. Acad. Sci., 44, 1929 (1959).
“Vital Statistics of the U.S.”, 1, 213 (1955).
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SZILARD, L. Dependence of the Sex Ratio at Birth on the Age of the Father. Nature 186, 649–650 (1960). https://doi.org/10.1038/186649a0
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DOI: https://doi.org/10.1038/186649a0
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