Abstract
IN 1952, Hodgkin and Huxley1 published a model which describes with considerable accuracy the electrical activity of nerve axons. The action potential in this tissue is accounted for by a large temporary increase in the permeability of the cell membrane, first to sodium ions, and then a millisecond or so later to potassium ions.
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References
Hodgkin, A. L., and Huxley, A. F., J. Physiol., 117, 500 (1952).
Weidmann, S., “Elecktrophysiologie der Herzmuskelfaser” (Huber, Bern, 1956).
Tasaki, I., and Hagiwara, S., J. Gen. Physiol., 40, 859 (1957).
Tasaki, I., J. Physiol., 148, 306 (1959).
Tasaki, I., and Spyropoulos, C. S., Amer. J. Physiol., 193, 318 (1958).
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GEORGE, E. Action Potentials in Active Tissue with Delayed Potassium Permeability. Nature 186, 889–890 (1960). https://doi.org/10.1038/186889a0
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DOI: https://doi.org/10.1038/186889a0
