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Fœtal Hæmoglobin in the Monkey

Nature volume 186, pages 977–978 (1960)Cite this article

Abstract

SOME well-known physico-chemical differences between human adult and fœtal hæmoglobin prompted us to find if similar differences exist between hæmoglobins from adult and new-born monkeys. The present communication describes the examination of the blood of 8 adult and 4 new-born monkeys (Macacus rhesus of North India) by the alkali resistance test and paper electrophoresis. Pregnant monkeys were obtained and were delivered in the cage to provide the new-born monkeys. Heart blood from the new-born and venous blood from the adult monkeys was collected in citrate solution. The alkali denaturation method of Singer et al. 1 was employed for determining the proportion of alkali-resistant hæmoglobin. Electrophoresis was carried out in ‘Elphor’ apparatus using paper strip No. 2043 a Mg 1 at 250 V. for a period of 16 hr. in veronal buffer of pH 8.6 and ionic strength 0.05.

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References

  1. Singer, K., Chernoff, A. I., and Singer, L., Blood, 6, 413 (1951).

    CAS  PubMed  Google Scholar 

  2. Jacob, G. F., and Tappen, N. C., Nature, 181, 197 (1958).

    Article  ADS  CAS  Google Scholar 

  3. Beaven, G. H., and Gratzer, W. B., Nature, 184, 1730 (1959).

    Article  ADS  Google Scholar 

  4. Sen, N. N., Mukherjee, C. L., Das, K. C., and Aikat, B. K., Bull. Inst., P.G. Med. Ed. Res., 1, 88 (1959).

    Google Scholar 

  5. Beaven, G. H., Hoch, H., and Holiday, E. R., Biochem. J., 49, 374 (1951).

    Article  CAS  Google Scholar 

  6. Beaven, G. H., Ellis, M., and White, J. C., Nature, 178, 857 (1956).

    Article  ADS  CAS  Google Scholar 

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Authors and Affiliations

  1. Division of Hæmatology, Department of Pathology and Bacteriology, Institute of Post Graduate Medical Education and Research, Calcutta, 20

    N. N. SEN, K. C. DAS & B. K. AIKAT

Authors
  1. N. N. SEN
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  2. K. C. DAS
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  3. B. K. AIKAT
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SEN, N., DAS, K. & AIKAT, B. Fœtal Hæmoglobin in the Monkey. Nature 186, 977–978 (1960). https://doi.org/10.1038/186977a0

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