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Distribution of Protein-bound Aminoazo Dyes in the Rat Liver Microsome

Nature volume 187, page 943 (1960)Cite this article

Abstract

EVIDENCE has been obtained that rat liver microsomes are the site where the formation of protein-bound aminoazo dyes occurs1‐3. On the other hand, one of the most important parts played by the microsome is known to be protein synthesis. Littlefield et al. 4 further fractionated the microsome by means of sodium deoxycholate and pointed out that the protein in the deoxycholate-insoluble fraction, ribonucleoprotein particles, showed a particularly high turn-over rate, suggesting that protein is in fact-synthesized in this fraction. This suggestion was supported by other authors5–7.

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Authors and Affiliations

  1. Department of Biophysics and Biochemistry, Faculty of Science, University of Tokyo, Tokyo

    T. YAMADA, M. MATSUMOTO, S. KANDA & H. TERAYAMA

Authors
  1. T. YAMADA
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  2. M. MATSUMOTO
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  3. S. KANDA
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  4. H. TERAYAMA
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YAMADA, T., MATSUMOTO, M., KANDA, S. et al. Distribution of Protein-bound Aminoazo Dyes in the Rat Liver Microsome. Nature 187, 943 (1960). https://doi.org/10.1038/187943a0

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