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In vitro Uptake of Iodine-131 by Tissues of Rainbow Trout

Abstract

RECENTLY, it has been shown that in vitro uptake of iodine-131 by the lactating mammary tissue of rat was 10–15 times that of liver, muscle or boiled mammary tissue. Further, the data on the in vitro uptake of iodine-131 by different tissues of rat indicate that iodide concentration mechanism in the mammary, salivary and gastric glands but not in liver or placenta appears to be similar to that of thyroid gland in the rat2. In the case of fish, it has been shown that the thyroid hormone is not involved in the regulation of oxidative metabolism, and thus it was decided to study the in vitro uptake of iodine-131 by different tissues of rainbow trout (Salmo gairdnerii)3. Tissue slices from one-year-old rainbow trout were incubated for 2 hr. at 13° C. in flasks containing 2 ml. Nandi and Bern medium4. The T/M values (counts per min. per 100 ml. tissue divided by counts per min. per 0.1 ml. medium) for different tissues were calculated.

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References

  1. Maqsood, M., and Reineke, E. P., Fed. Proc., 19, 172 (1960).

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  2. Maqsood, M., and Reineke, E. P., Nature (in the press).

  3. Hoar, W. S., Canad. J. Zool., 36, 113 (1958).

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  4. Nandi, J., and Bern, H. A., Endocrinol., 66, 295 (1960).

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MAQSOOD, M., REINEKE, E. & FROMM, P. In vitro Uptake of Iodine-131 by Tissues of Rainbow Trout. Nature 188, 1030–1031 (1960). https://doi.org/10.1038/1881030a0

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