Abstract
WITH the technique for polio vaccine production used at present, the end-point titres often are in the neighbourhood of 106/ml., which is recommended as the lowest limit. Different methods have been tested to find a simple way for concentration of the virus. The physical and chemical methods proposed so far are rather complicated and give a comparatively low yield of virus1. Variations in the technique for cultivation of the virus have also been suggested as a means of increasing the virus titres2.
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NORRBY, E., ALBERTSSON, P. Concentration of Poliovirus by an Aqueous Polymer Two-Phase System. Nature 188, 1047–1048 (1960). https://doi.org/10.1038/1881047a0
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DOI: https://doi.org/10.1038/1881047a0
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