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Absorption and Excretion of Copper in Mice

Abstract

THE marked elevation of tissue copper that occurs in Wilson's disease is generally thought to be due to an increased absorption of copper from the gastrointestinal tract1,2. In the work reported here, this concept was re-examined.

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References

  1. Bearn, A. G., and Kunkel, H. G., J. Lab. and Clin. Med., 45, 623 (1955).

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  2. Bush, J. A., Mahoney, J. P., Markowitz, H., Gubler, C. J., Cartwright, G. E., and Wintrobe, M. M., J. Clin. Invest., 34, 1766 (1955).

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  3. Denny-Brown, D., and Porter, H., New England J. Med., 245, 917 (1951).

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GITLIN, D., HUGHES, W. & JANEWAY, C. Absorption and Excretion of Copper in Mice. Nature 188, 150–151 (1960). https://doi.org/10.1038/188150a0

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