Abstract
PURIFIED pyruvate decarboxylase from brewer's yeast1 is not only capable of decarboxylating pyruvate to acetaldehyde and carbon dioxide2, but can also catalyse the oxidation of pyruvate to acetate with 2,6-dichlorophenolindophenol as artificial hydrogen acceptor3. Ferricyanide cannot act as a hydrogen acceptor with pyruvate decarboxylase irrespective of whether the enzyme is prepared from yeast3 or wheat germ4.
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References
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HOLZER, H., CRAWFORD, R. Phenazine Methosulphate as a Mediator in the Oxidation of Pyruvate by Pyruvate Decarboxylase from Brewer's Yeast. Nature 188, 410–411 (1960). https://doi.org/10.1038/188410a0
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DOI: https://doi.org/10.1038/188410a0
