Abstract
CERTAIN effects of X-irradiation of the exteriorized or in situ intestine of Sprague–Dawley rats were previously reported from these Laboratories1. In view of the scarcity of information concerning the occurrence of tumours after exposure of the intestine to irradiation, survivors of that study, and their controls were kept for further observation. This communication reports the incidence of intestinal tumours among 51 rats that were irradiated at an age of 5 months and were killed between 9 and 30 months later. All but seven experimental and two control animals were killed because of the presence of tumours or other diseases. The nine rats were arbitrarily killed at an age of ten months at the conclusion of the period of experimentation.
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Sullivan, M. F., Marks, S., Hackett, P. L., and Thompson, R. C., Rad. Res., 11, 653 (1959).
Osborne, J. W., Nicholson, D. P., and Solem, R., Rad. Res., 12, 460 (1960).
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MARKS, S., SULLIVAN, M. Tumours of the Small Intestine in Rats after Intestinal X-Irradiation. Nature 188, 953 (1960). https://doi.org/10.1038/188953a0
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DOI: https://doi.org/10.1038/188953a0
