Abstract
THE unsolved question of the source of many human congenital anomalies has recently received great impetus from the cytological aspect. This is largely due to an improved chromosome spreading technique which led to the establishment of the correct chromosome number in man1. Further evidence that a change in chromosome number was responsible for the phenotypic expression of certain clinical entities2 stimulated the application of this approach to cases of cerebral palsy of unknown or so-called developmental etiology.
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References
Tjio, J. H., and Levan, A., Hereditas, 42, 1 (1956). Ford, C. E., and Hamerton, J. L., Nature, 178, 1020 (1956).
Ford, C. E., et al., Nature, 183, 1030 (1959). Sasaki, M., and Makino, S., Texas Rep. Biol. and Med., 18, 493 (1960).
Blumel, J., et al., A.M.A. Arch. Ophth., 63, 246 (1960).
Hungerford, D. A., et al., Amer. J. Human Genetics, 11, 215 (1959).
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BLUMEL, J., OHNUKI, Y. & AWA, A. Chromosome Anomaly in Two Cases of Cerebral Palsy, a Brother and a Sister. Nature 189, 154–155 (1961). https://doi.org/10.1038/189154a0
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DOI: https://doi.org/10.1038/189154a0
