Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Letter
  • Published:

Replacement of Adrenaline and Noradrenaline in the Adrenal Gland of the Rat, following Depletion and Redepletion with Reserpine

Abstract

IN a previous communication1, we showed that reserpine causes a similar percentage loss of adrenaline and noradrenaline from the adrenal glands of the rat. Recovery of the catechol amines was slow, the amine content returning to normal within 21 days. The adrenaline content gradually returned to the control value, whereas the noradrenaline content first increased rapidly to a level well above normal at 7 days before falling to the control value.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Similar content being viewed by others

References

  1. Callingham, B. A., and Mann, M., Nature, 181, 423 (1958).

    Article  ADS  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

CALLINGHAM, B., MANN, M. Replacement of Adrenaline and Noradrenaline in the Adrenal Gland of the Rat, following Depletion and Redepletion with Reserpine. Nature 190, 1201 (1961). https://doi.org/10.1038/1901201a0

Download citation

  • Issue date:

  • DOI: https://doi.org/10.1038/1901201a0

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing