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Aggregation of Protein Particles in Tumour Cells

Nature volume 190, pages 358–359 (1961)Cite this article

Abstract

IN the cytoplasm of the cells of some tumours (Ehrlich ascites tumour, Yoshida ascites tumour, Walker carcinoma, hepatoma of the rat and human malignant lymphogranuloma) a form of dispersion of the ribosomes has been seen1–3 at the electron microscope described4–6 as ‘scattered’ or ‘unorganized ergastoplasm’. A similar condition also occurs3,7 during the previtellogenesis of the oocytes in some animal species (Haliotis lamellosa, Paracentrotus lividus, Sphaerechinus granularis, Arbacia lixula). While in tumour cells ‘scattered ergastoplasm’ persists, it is seen8 that in the oocytes the ribosomes, after having increased and probably having undergone a transformation, aggregate during vitellogenesis to make yolk globules (Figs. 1 and 4).

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Authors and Affiliations

  1. Istituto di Zoologia e di Anatomia comparata, Università di Messina,

    A. BOLOGNARI

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  1. A. BOLOGNARI
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BOLOGNARI, A. Aggregation of Protein Particles in Tumour Cells. Nature 190, 358–359 (1961). https://doi.org/10.1038/190358a0

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