Abstract
COLICINES are unique among antibiotics in being specifically adsorbed on to the surface of bacteria in a manner analogous to antibodies and bacteriophages. Besides being removed from solution by adsorption on sensitive bacteria1, they can be inactivated by extracts of sensitive, but not of resistant, organisms2. The nature of colicine receptors on the bacterial surface has not so far been elucidated. This communication describes some preliminary observations on the subject.
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References
Jacob, F., Siminovitch, L., and Wollman, E., Ann. Inst. Pasteur, 83, 295 (1952).
Bordet, P., and Beumer, J., C.R. Soc. Biol., 142, 259 (1948).
van Horn, Elizabeth A., M.Sc. thesis, University of Bristol (1961).
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MAYR-HARTING, A. Nature of Colicine Receptors. Nature 192, 191 (1961). https://doi.org/10.1038/192191a0
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DOI: https://doi.org/10.1038/192191a0
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