Abstract
A PAPER now in the press1 shows that the heart accelerating factor from the corpus cardiacum of the cockroach Periplaneta americana described by Cameron2,3 acts by stimulating the pericardial cells to produce a second substance. It is this pericardial cell factor which is responsible for the direct stimulation of the heart. This communication describes the properties of the two substances.
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References
Davey, K. G., Gen. Comp. Endocrinol. (in the press).
Cameron, M. L., Dissertation, Cambridge (1953).
Cameron, M. L., Nature, 172, 349 (1953).
Davey, K. G., Canad. J. Zool., 38, 717 (1960).
Weissbach, H. H., Waalkes, T. P., and Udenfriend, S., J. Biol. Chem., 230, 865 (1958).
Jepson, J. B., and Stevens, B. J., Nature, 172, 772 (1953).
Davey, K. G., Canad. J. Zool., 38, 39 (1960).
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DAVEY, K. Substances controlling the Rate of Beating of the Heart of Periplaneta. Nature 192, 284 (1961). https://doi.org/10.1038/192284a0
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DOI: https://doi.org/10.1038/192284a0
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