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Activity of Deoxyribonuclease as related to Root-Growth

Nature volume 192, pages 371–372 (1961)Cite this article

Abstract

IT has been repeatedly observed in the past few years that deoxyribonuclease (DNase) activity is increased in normal growing animal tissues1–5. As postulated by Brody2, it is possible that the increase in acid DNase activity counterbalances the greatly enhanced activity of the deoxyribonucleic acid (DNA) synthesizing enzymes and indeed determines the normal character of the growth. Cancerous tissues, on the contrary, have a lower DNase activity, at least when the activity is expressed per mgm. DNA (ref. 2), but not, apparently, when it is expressed per mgm. nitrogen6.

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References

  1. Siebert, G., Lang, K., Lucius-Lang, S., Herkert, L., Stark, G., Rossmüller, G., and Jöckel, H., Z. physiol. Chem., 295, 229 (1953).

    Article  CAS  Google Scholar 

  2. Brody, S., and Balis, M. E., Nature, 182, 940 (1958).

    Article  ADS  CAS  PubMed  Google Scholar 

  3. Brody, S., Nature, 182, 1386 (1958).

    Article  CAS  PubMed  Google Scholar 

  4. Brody, S., and Balis, M. E., Cancer Res., 19, 538 (1959).

    CAS  PubMed  Google Scholar 

  5. Goutier, R., Goutier-Pirotte, M., and Ciccarone, P., Intern. J. Rad. Biol., 2, Supp. 1, 93 (1960).

    Google Scholar 

  6. Deckers-Passau, L., Maisin, J., and de Duve, C., Acta Un. Intern. contre Cancer, 13, 822 (1957).

    CAS  Google Scholar 

  7. Laskowsky, M., and Seidel, M. K., Arch. Biochem., 7, 465 (1945)

    Google Scholar 

  8. Kay, R. M., Simmons, N. S., and Dounce, A. L., J. Amer. Chem. Soc., 74, 1724 (1952).

    Article  CAS  Google Scholar 

  9. Ogur, M., and Rosen, G., Arch. Biochem., 25, 262 (1950).

    CAS  PubMed  Google Scholar 

  10. Burton, K., Biochem. J., 62, 315 (1956).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  11. Jensen, W. A., Exp. Cell Res., 14, 575 (1958).

    Article  CAS  PubMed  Google Scholar 

  12. Südi, J., and Maroti, M., Acta Bot. Acad. Sci., Hungary, 3, 65 (1957).

    Google Scholar 

  13. Pelc, S. R., and LaCour, L. F., Experientia, 15, 131 (1959).

    Article  CAS  PubMed  Google Scholar 

Download references

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Authors and Affiliations

  1. Laboratoire de Radiobiologie, Centre d'Etude de l'Energie Nucléaire, Mol, Belgium

    R. GOUTIER & M. GOUTIER-PIROTTE

Authors
  1. R. GOUTIER
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  2. M. GOUTIER-PIROTTE
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GOUTIER, R., GOUTIER-PIROTTE, M. Activity of Deoxyribonuclease as related to Root-Growth. Nature 192, 371–372 (1961). https://doi.org/10.1038/192371a0

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