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Sexual Differentiation of the Mullerian Ducts of the Chick Embryo

Nature volume 193, pages 88–89 (1962)Cite this article

Abstract

WOLFF1,2 and others have interpreted in vitro evidence to mean that Mullerian ducts of the chick embryo undergo involution as a result of androgen-activation of an intracellular proteolytic enzyme specific to the ducts. Brachet et al.3 have reported for the two male and the right female Mullerian ducts undergoing involution a marked progressive rise in ribonuclease, acid phosphatase, and cathepsin in comparison to the left female duct, which is normally stable during differentiation. This preliminary communication is designed to consider such findings in the light of the work at present being done on the mechanism of steroid hormone action and to outline the direction of experiments now in progress in my laboratory.

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Authors and Affiliations

  1. Harvard Biological Laboratories, Cambridge, Massachusetts

    TERRELL H. HAMILTON

  2. Department of Zoology, University of Texas, Austin, Texas

    TERRELL H. HAMILTON

Authors
  1. TERRELL H. HAMILTON
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HAMILTON, T. Sexual Differentiation of the Mullerian Ducts of the Chick Embryo. Nature 193, 88–89 (1962). https://doi.org/10.1038/193088a0

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